Description
DB2313 tetrahydrochloride is a potent transcription factor PU.1 inhibitor with an apoptosis of 14 nM. DB2313 tetrahydrochloride disrupts the interaction of PU.1 with target gene promoters. DB2313 tetrahydrochloride induces apoptosis of acute myeloid leukemia (AML) cells, and has anticancer effects.
Product information
CAS Number: 2170606-75-2
Molecular Weight: 854.67
Formula: C42H45Cl4FN8O2
Smiles: Cl.Cl.Cl.Cl.CC(C)NC(=N)C1C=C2NC(=NC2=CC=1)C1C=CC(=CC=1)OCC1C=CC=C(COC2C=CC(=CC=2)C2NC3C=C(C=CC=3N=2)C(=N)NC(C)C)C=1F
InChiKey: VTQBTZDMPNTLGK-UHFFFAOYSA-N
InChi: InChI=1S/C42H41FN8O2.4ClH/c1-24(2)46-39(44)28-12-18-34-36(20-28)50-41(48-34)26-8-14-32(15-9-26)52-22-30-6-5-7-31(38(30)43)23-53-33-16-10-27(11-17-33)42-49-35-19-13-29(21-37(35)51-42)40(45)47-25(3)4;;;;/h5-21,24-25H,22-23H2,1-4H3,(H2,44,46)(H2,45,47)(H,48,50)(H,49,51);4*1H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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