Description
LTI-291 is a glucocerebrosidase (Gcase) activator for treatment of Parkinson's disease (PD).
Product information
CAS Number: 1919820-28-2
Molecular Weight: 358.48
Formula: C20H30N4O2
Synonym:
LTI 291
LTI291
LTI-291
Chemical Name: 5,7-Dimethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (trans-4-pentyloxy-cyclohexyl)-amide
Smiles: CCCCCO[C@@H]1CC[C@H](CC1)NC(=O)C1C=NN2C=1N=C(C)C=C2C
InChiKey: HZILSILAELSWKN-QAQDUYKDSA-N
InChi: InChI=1S/C20H30N4O2/c1-4-5-6-11-26-17-9-7-16(8-10-17)23-20(25)18-13-21-24-15(3)12-14(2)22-19(18)24/h12-13,16-17H,4-11H2,1-3H3,(H,23,25)/t16-,17-
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 50 mg/mL (139.48 mM; Need ultrasonic)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined.
HS Tariff Code: 382200
References:
- Renato T. Skerlj, et al. Methods of treatment and combination therapies using gcase activator heterobicyclic and related compounds. WO 2017192841 A1.
Products are for research use only. Not for human use.
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