Description
PPQ-102 is a potent and voltage-independent CFTR inhibitor which completely inhibit CFTR chloride current with IC50 approximately 90 nM
Product information
CAS Number: 931706-15-9
Molecular Weight: 438.48
Formula: C26H22N4O3
Chemical Name: 7,9-dimethyl-6-(5-methylfuran-2-yl)-11-phenyl-5,6-dihydropyrimido[4',5':3,4]pyrrolo[1,2-a]quinoxaline-8,10(7H,9H)-dione
Smiles: CC1=CC=C(O1)C1NC2=CC=CC=C2N2C(=C3C(=C21)N(C)C(=O)N(C)C3=O)C1C=CC=CC=1
InChiKey: MNOOVRNGPIWJDI-UHFFFAOYSA-N
InChi: InChI=1S/C26H22N4O3/c1-15-13-14-19(33-15)21-24-23-20(25(31)29(3)26(32)28(23)2)22(16-9-5-4-6-10-16)30(24)18-12-8-7-11-17(18)27-21/h4-14,21,27H,1-3H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO: 50 mg/mL(114.03 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Lukmanee Tradtrantip, et al. J Med Chem. 2009 Oct 22;52(20):6447-55.
Products are for research use only. Not for human use.
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