Description
EMAC10101d is a potent and selective inhibitor of Carbonic Anhydrase Isoform toward hCA II with an inhibitory activity in the low nanomolar range.
Product information
CAS Number: 2561476-24-0
Molecular Weight: 428.36
Formula: C17H15Cl2N3O2S2
Synonym:
EMAC-10101d
Chemical Name: 4-{[4-(2, 4-dichlorophenyl)-3-ethyl-2, 3-dihydro-1, 3-thiazol-2-ylidene]amino}benzene-1-sulfonamide
Smiles: CCN1C(=NC2C=CC(=CC=2)S(N)(=O)=O)SC=C1C1=CC=C(Cl)C=C1Cl
InChiKey: OEGLVUQKHJHUEU-FXBPSFAMSA-N
InChi: InChI=1S/C17H15Cl2N3O2S2/c1-2-22-16(14-8-3-11(18)9-15(14)19)10-25-17(22)21-12-4-6-13(7-5-12)26(20,23)24/h3-10H,2H2,1H3,(H2,20,23,24)/b21-17-
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Meleddu R , Distinto S , Cottiglia F , et al. New Dihydrothiazole Benzensulfonamides: Looking for Selectivity toward Carbonic Anhydrase Isoforms I, II, IX, and XII[J]. ACS Medicinal Chemistry Letters, 2020, XXXX(XXX).
Products are for research use only. Not for human use.
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