Description
Losartan D4 (DuP-753 D4) is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.
Product information
CAS Number: 1030937-27-9
Molecular Weight: 426.94
Formula: C22H23ClN6O
Synonym:
DuP-753 D4
Cozaar D4
Chemical Name: (2-butyl-4-chloro-1-{[2'-(2H-1,2,3,4-tetrazol-5-yl)(2,3,5,6-²H₄)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol
Smiles: [2H]C1C(C2=CC=CC=C2C2=NNN=N2)=C([2H])C([2H])=C(CN2C(CO)=C(Cl)N=C2CCCC)C=1[2H]
InChiKey: PSIFNNKUMBGKDQ-IRYCTXJYSA-N
InChi: InChI=1S/C22H23ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28)/i9D,10D,11D,12D
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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