ML-7 Hydrochloride


Catalog No. Size PriceQuantity
M10114-2 Solid 2 mg $90
M10114-10 Solid 10 mg $270

Description

ML-7 is a MLCK inhibitor. ML-7 inhibits smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 µM. ML-7 amplifies the quinocetone-induced cell death through akt and MAPK-mediated apoptosis on HepG2 cell line. ML-7 inhibits exocytosis of superoxide-producing intracellular compartments in human neutrophils stimulated with phorbol myristate acetate in a myosin light chain kinase-independent manner.

Product information

CAS Number: 110448-33-4

Molecular Weight: 452.74

Formula: C15H18ClIN2O2S

Chemical Name: 1-[(5-iodonaphthalen-1-yl)sulfonyl]-1,4-diazepane hydrochloride

Smiles: Cl.O=S(=O)(C1=CC=CC2=C(I)C=CC=C21)N1CCCNCC1

InChiKey: KDDALCDYHZIZMH-UHFFFAOYSA-N

InChi: InChI=1S/C15H17IN2O2S.ClH/c16-14-6-1-5-13-12(14)4-2-7-15(13)21(19,20)18-10-3-8-17-9-11-18;/h1-2,4-7,17H,3,8-11H2;1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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