Description
IRAK4-IN-7 is a selective, potent and orally active interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor, extracted from patent WO2015104688 (example 1). IRAK4-IN-7 has the potential for cancer and inflammatory diseases treatment.
Product information
CAS Number: 1801343-74-7
Molecular Weight: 417.42
Formula: C21H19N7O3
Chemical Name: 6'-amino-N-(2-morpholinooxazolo[4, 5-b]pyridin-6-yl)-[2, 3'-bipyridine]-6-carboxamide
Smiles: NC1=CC=C(C=N1)C1C=CC=C(N=1)C(=O)NC1=CN=C2N=C(OC2=C1)N1CCOCC1
InChiKey: RWIMETUXCNDSLE-UHFFFAOYSA-N
InChi: InChI=1S/C21H19N7O3/c22-18-5-4-13(11-23-18)15-2-1-3-16(26-15)20(29)25-14-10-17-19(24-12-14)27-21(31-17)28-6-8-30-9-7-28/h1-5,10-12H,6-9H2,(H2,22,23)(H,25,29)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 13.89 mg/mL (33.28 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
IRAK4-IN-7 has anti-cancer and anti-inflammatory activities, it can be used for cancer and inflammatory diseases treatment.
Products are for research use only. Not for human use.
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